FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Raizen Energia Participacoes S.A.
 2. Date of Event Requiring Statement (Month/Day/Year)
06/01/2011		 3. Issuer Name and Ticker or Trading Symbol
CODEXIS INC [CDXS]
(Last)
(First)
(Middle)
AVENIDA PRESIDENTE JUSCELINO KUBITSCHECK, 1327 6 O ANDAR		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

SAO PAULO, D5 04543-011		 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 5,573,319 (1)
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Raizen Energia Participacoes S.A.
AVENIDA PRESIDENTE JUSCELINO KUBITSCHECK
1327 6 O ANDAR
SAO PAULO, D5 04543-011		     X    
Ispagnac Participacoes Ltda.
AVENIDA DAS AMERICAS 4200 BLOCO 6,
1 O ANDAR, (PART) BARRA DA TIJUCA
RIO DE JANEIRO, RJ CEP, D5 22640-102		     X    
Royal Dutch Shell plc
30, CAREL VAN BYLANDTLAAN
THE HAGUE, P7 2596 HR		     X    
Cosan S.A. Industria e Comercio
AVENIDA PRESIDENTE JUSCELINO KUBITSCHEK,
1327, 4 O ANDAR
SAO PAULO, SP CEP, D5 04543-011		     X    
Cosan Ltd.
AVENIDA PRESIDENTE JUSCELINO KUBITSCHEK,
1726 6TH FLOOR
SAO PAULO, SP, D5 04543-000		     X    

Signatures

/s/ Pedro Isamu Mizutani for Raizen Energia Participacoes S.A as its COO 06/01/2011
**Signature of Reporting Person Date
/s/ Matias Lopes for Ispagnac Participacoes Ltda as an Officer 06/01/2011
**Signature of Reporting Person Date
/s/ Mark Edwards for Royal Dutch Shell plc as its Deputy Company Secretary 06/01/2011
**Signature of Reporting Person Date
/s/ Marcos Marinho Lutz for Cosan S.A. Industria e Comercio as its CEO 06/01/2011
**Signature of Reporting Person Date
/s/ Rubens Ometo Silveira Mello for Cosan Limited as its CEO 06/01/2011
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) (1) Acquisition of Codexis Common Stock by Raizen Energia Participacoes S.A. ("Raizen"), a joint venture company in which Royal Dutch Shell plc ("RDS") and Cosan Limited are indirectly, through their respective subsidiaries Ispagnac Participacoes Ltda. ("Ispagnac") and Cosan S.A. Industria e Comercio, joint venture partners, from Ispagnac was part of RDS's and its affiliates' contribution to such joint venture, and was made in exchange for Raizen capital stock.

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