Exhibit 99.1

 

LOGO     Codexis, Inc.
    200 Penobscot Drive
    Redwood City, CA 94063
   

Tel: 650.421.8100

www.codexis.com

CODEXIS ANNOUNCES FIRST QUARTER 2011 RESULTS

Codexis Reports First Quarter 2011 Results

Grows Revenue 21% to $31 million;

106% Increase in Pharmaceutical Product Sales

Redwood City, CA – May 5, 2011 – Codexis, Inc. (NASDAQ: CDXS) today announced financial results for the first quarter ended March 31, 2011.

First Quarter Financial Highlights:

Revenue: For the first quarter of 2011, the company reported revenues of $31.0 million, an increase of 21% from $25.7 million in the first quarter of 2010. Product revenue of $12.9 million increased 106% over the same time period driven by more than $5 million in sales of the boceprevir intermediate to be used in Merck’s investigational Hepatitis C drug trade named Victrelis. Collaborative R&D revenue of $2.7 million increased from $0.7 million in the first quarter of 2010, driven mainly by funded research for our carbon capture program.

Operating Expenses: Research and development expenses in the first quarter of 2011 were $13.8 million, compared to $13.0 million for the first quarter of 2010. The increase was primarily due to an increase in amortization related to intellectual property purchased from Maxygen, Inc. in the fourth quarter of 2010 and higher depreciation and stock compensation expenses. Selling, general and administrative expenses in the first quarter of 2011 increased to $9.0 million compared to $8.6 million over the same period of 2010, driven by higher stock compensation expense and higher compensation expense due to headcount increases.

Net Loss: Net loss was ($3.5) million, or ($0.10) per share, based on 35.1 million weighted average common shares outstanding in the first quarter of 2011. This compares to a net loss of ($1.4) million or ($0.50) per share during the first quarter of 2010.

Adjusted EBITDA: On a non-GAAP basis, Adjusted EBITDA decreased from $2.8 million in the first quarter of 2010 to $1.8 million in 2011. Adjusted EBITDA is calculated by adjusting net loss for net interest expense, income taxes, depreciation, amortization, stock-based compensation and preferred stock warrant fair market valuation. A reconciliation of net loss to Adjusted EBITDA is presented below.

Cash: Cash, cash equivalents and marketable securities at March 31, 2011, increased to $82.0 million compared to $74.0 million at December 31, 2010. The company generated $7.3 million in cash from operations in the first quarter.

 

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Outlook

Codexis’ statements with regard to its outlook are based on current expectations. The following statements are forward looking, and actual results could differ materially depending on market conditions and the factors set forth under “Forward-Looking Statements” below.

For the full year 2011, Codexis forecasts revenues of $120 million or greater, which would represent growth of 12% or greater compared to 2010. Codexis expects 2011 Adjusted EBITDA will be $5 million or greater.

Recent Events

On April 7, 2011, Codexis announced a partnership with Alcoa and CO2 Solution, Inc. for a carbon capture technology pilot test designed to turn emissions into beneficial commercial products. The collaboration will use proprietary enzyme technologies to reduce the environmental impact of industrial byproducts. This new pilot program will be funded by Alcoa and includes $13.5 million from the U.S. Department of Energy.

On March 8, 2011, Codexis named Jacques Beaudry-Losique VP Corporate Development & Strategy. Mr. Beaudry-Losique joined Codexis from the U.S. Department of Energy, and is responsible for corporate strategic planning for Codexis’ bioindustrials businesses and directing the company’s government relations programs.

On February 17, 2011, Codexis announced that Byron Dorgan, former U.S. Senator from North Dakota, had been elected to the company’s Board of Directors. Senator Dorgan retired from the Senate in January 2011 after a 30-year career in the U.S. Congress.

On January 25, 2011, Codexis signed its first Japanese biocatalysis collaboration with Dainippon Sumitomo Pharma, one of the ten largest Japanese pharmaceutical manufacturers. Under the agreement, Codexis will supply biocatalysis screening products and services to DSP for use in selected undisclosed therapeutic products in its development pipeline.

On January 12, 2011, Codexis signed an enzyme supply agreement with DSM Pharmaceutical Products, the custom manufacturing organization of Royal DSM NV. The agreement grants DSM rights to use Codexis’ custom biocatalysts and services, and secures supply of Codexis enzymes for commercialization of sustainable enzyme-based pharmaceutical manufacturing routes developed by DSM’s InnoSyn™ route scouting services.

Conference Call

Codexis will hold a conference call for investors on May 5, 2011 at 1:30 p.m. PT (4:30 p.m. ET). The conference call dial-in numbers are US: 866-730-5771 or International: 857-350-1595, access code 43195209. A live webcast of the call will also be available from the Investor Relations section of www.codexis.com. A recording of the call will be available by calling US: 888-286-8010 or International: 617-801-6888, access code 62515565 beginning approximately two hours after the call, and will be available for up to thirty days. A webcast replay from today’s call will also be available from the Investor Relations section of www.codexis.com approximately two hours after the call and will be available for up to thirty days.

 

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About Codexis, Inc.

Codexis is a clean technology company. Codexis develops optimized biocatalysts that make industrial processes faster, cleaner and more efficient. Codexis’ technology is commercialized with leading global pharmaceutical companies and in development for advanced biofuels with Shell and carbon capture. Other potential markets for the company’s biocatalyst-enabled solutions include chemicals and water treatment.

Forward-Looking Statements

This press release contains forward-looking statements relating to the company’s forecast for 2011 revenue and Adjusted EBITDA, which is defined elsewhere in this press release. You should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties and other factors that are, in some cases, beyond our control and that could materially affect actual results. Factors that could materially affect actual results can be found in Codexis’ Annual Report on Form 10-K filed with the Securities and Exchange Commission on February 10, 2011, including under the caption “Risk Factors.” Codexis expressly disclaims any intent or obligation to update these forward-looking statements, except as required by law.

 

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Codexis, Inc.

Condensed Consolidated Statements of Operations

(Unaudited)

(In Thousands, Except Per Share Amounts)

 

     Three Months Ended
March 31,
       
     2011     2010     % change  

Revenues:

      

Product

   $ 12,932      $ 6,275        106

Related party collaborative research and development

     14,823        16,042        -8

Collaborative research and development

     2,663        661        303

Government grants

     616        2,722        -77
                  

Total revenues

     31,034        25,700        21
                  

Costs and operating expenses:

      

Cost of product revenues

     11,650        5,218        123

Gross margin $

     1,282        1,057     

Gross margin %

     10     17  

Research and development

     13,750        12,982        6

Selling, general and administrative

     9,013        8,600        5
                  

Total costs and operating expenses

     34,413        26,800        28
                  

Loss from operations

     (3,379     (1,100     207

Interest income

     49        28        75

Interest expense and other, net

     17        (358     nm   
                  

Loss before provision (benefit) for income taxes

     (3,313     (1,430     132

Provision (benefit) for income taxes

     158        (61     nm   
                  

Net loss

   $ (3,471   $ (1,369     154
                  

Net loss per share of common stock, basic and diluted

   $ (0.10   $ (0.50  
                  

Weighted average common shares used in computing net loss per share of common stock, basic and diluted

     35,116        2,714     
                  

 

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Codexis, Inc.

Condensed Consolidated Balance Sheets

(Unaudited)

(In Thousands)

 

     March 31,
2011
    December 31,
2010
 

Assets

    

Current assets:

    

Cash and cash equivalents

   $ 53,152      $ 72,396   

Marketable securities

     12,540        —     

Accounts receivable, net

     11,322        10,620   

Related party accounts receivable

     —          4,713   

Inventories

     3,224        2,817   

Prepaid expenses and other current assets

     2,617        1,646   
                

Total current assets

     82,855        92,192   

Restricted cash

     1,512        1,466   

Long-term marketable securities

     16,296        1,650   

Property and equipment, net

     20,239        21,452   

Intangible assets, net

     19,230        20,158   

Goodwill

     3,241        3,241   

Other non-current assets

     1,175        1,141   
                

Total assets

   $ 144,548      $ 141,300   
                

Liabilities and shareholders’ equity

    

Current liabilities:

    

Accounts payable

   $ 10,245      $ 9,208   

Accrued compensation

     3,784        8,107   

Other accrued liabilities

     7,450        5,630   

Deferred revenues

     770        455   

Related party deferred revenues

     8,691        4,084   
                

Total current liabilities

     30,940        27,484   

Deferred revenues, net of current portion

     1,625        1,671   

Related party deferred revenues, net of current portion

     2,382        3,403   

Other long-term liabilities

     1,595        1,381   
                

Total liabilities

     36,542        33,939   

Stockholders’ equity:

    

Common stock

     4        4   

Additional paid-in capital

     279,574        275,540   

Accumulated other comprehensive loss

     49        (34

Accumulated deficit

     (171,621     (168,149
                

Total stockholders’ equity

     108,006        107,361   
                

Total liabilities, and shareholders’ equity

   $ 144,548      $ 141,300   
                

 

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Codexis, Inc.

Condensed Consolidated Statements of Cash Flow

(Unaudited)

(In Thousands)

 

     Three Months Ended
March 31,
 
     2011     2010  

Operating activities:

    

Net loss

   $ (3,471   $ (1,369

Adjustments to reconcile net loss to net cash used in operating activities:

    

Amortization of intangible assets

     941        187   

Depreciation and amortization of property and equipment

     1,895        1,651   

Revaluation of redeemable convertible preferred stock warrant liability

     —          396   

Gain from extinguishment of asset retirement obligation

     (124     —     

Stock-based compensation

     2,307        1,655   

Accretion of asset retirement obligation

     17        36   

Amortization of debt discount

     —          24   

Accretion (amortization) of premium/discount on marketable securities

     (3     (119

Changes in operating assets and liabilities:

    

Accounts receivable

     4,011        685   

Inventories

     (407     3   

Prepaid expenses and other current assets

     (971     (261

Other assets

     (48     (71

Accounts payable

     1,037        (2,720

Accrued compensation

     (4,324     (2,958

Related party payable

     —          (766

Other accrued liabilities

     2,570        (1,372

Deferred revenues

     3,856        (7,026
                

Net cash provided by (used in) operating activities

     7,286        (12,025
                

Investing activities:

    

(Increase) decrease in restricted cash

     (46     —     

Purchase of property and equipment

     (891     (1,320

Purchase of marketable securities

     (27,104     —     

Proceeds from maturities of marketable securities

     —          13,610   
                

Net cash provided by (used in) investing activities

     (28,041     12,290   
                

Financing activities:

    

Principal payments on financing obligations

     —          (1,339

Payments in preparation for initial public offering

     —          (1,636

Proceeds from exercises of stock options

     1,485        140   
                

Net cash provided by (used in) financing activities

     1,485        (2,835
                

Effect of exchange rate changes on cash and cash equivalents

     26        (18
                

Net increase in cash and cash equivalents

     (19,244     (2,588

Cash and cash equivalents:

    

Beginning of the period

     72,396        31,785   
                

End of the period

     53,152        29,197   

Marketable securities at the end of period

     28,836        10,067   
                

Cash, cash equivalents and marketable securities

   $ 81,988      $ 39,264   
                

 

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Reconciliation of GAAP to Non-GAAP Financial Information

In this press release, in addition to GAAP financial results, we present Adjusted EBITDA because we believe it assists investors and analysts in comparing our performance across reporting periods on a consistent basis by excluding items that we do not believe are indicative of our core operating performance. In addition, we use Adjusted EBITDA to evaluate the effectiveness of our business strategies.

A reconciliation of GAAP net loss to Adjusted EBITDA is included in the table below.

Codexis, Inc.

Reconciliation of GAAP Net Loss to Adjusted EBITDA

(Unaudited)

(In Thousands)

 

     Three Months Ended
March 31,
 

Calculation of Adjusted EBITDA

   2011     2010  

Net loss

   $ (3,471   $ (1,369

Adjustments:

    

Minus: Interest income

     (49     (28

Plus: Interest expense

     —          298   

Plus: Income taxes

     158        (61

Plus: Depreciation and amortization

     2,836        1,838   

Plus: Stock-based compensation

     2,286        1,713   

Plus: Preferred stock warrant fair market valuation adjustment

     —          396   
                

Adjusted EBITDA

   $ 1,760      $ 2,787   
                

Adjusted EBITDA has limitations as an analytical tool. Some of these limitations are:

 

   

Adjusted EBITDA does not reflect our cash expenditures, or future requirements, for capital expenditures or contractual commitments;

 

   

Adjusted EBITDA does not reflect changes in, or cash requirements for, our working capital needs;

 

   

Although depreciation and amortization are non-cash charges, the assets being depreciated and amortized will often have to be replaced in the future, and Adjusted EBITDA does not reflect any cash requirements for such replacements; and

 

   

Non-cash compensation is and will remain a key element of our overall long-term incentive compensation package, although we exclude it as an expense when evaluating our ongoing operating performance for a particular period.

Because of these limitations, Adjusted EBITDA should not be considered in isolation or as a substitute for performance measures calculated in accordance with GAAP. We compensate for these limitations by relying primarily on our GAAP results and using Adjusted EBITDA only supplementally.

Contacts:

Investors: Henk Adriaenssens, ir@codexis.com, 650-421-8331

Media: Lyn Christenson, lyn.christenson@codexis.com, 650-421-8144 or Saskia Sidenfaden, ssidenfaden@mww.com, 212-827-3771.

 

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