Exhibit 99.1

LOGO

   Codexis, Inc.

200 Penobscot Drive

Redwood City, CA 94063
Tel: 650.421.8100

www.codexis.com

Codexis Reports Third Quarter 2011 Results

Revenue grows 23% year over year to $33 million

Redwood City, CA – November 1, 2011 – Codexis, Inc. (NASDAQ: CDXS) today announced financial results for the third quarter ended September 30, 2011.

Third Quarter Financial Highlights:

Revenue: For the third quarter of 2011, the company reported revenues of $33.3 million, an increase of 23% from $27.1 million in the third quarter of 2010. Product revenue of $12.2 million increased 29% over the prior year quarter driven primarily by an increase in product sales to both generic and innovator pharmaceutical customers. Collaborative R&D revenue of $19.2 million increased from $17.2 million in the third quarter of 2010, driven mainly by milestones earned in the company’s Shell collaboration and by funded research for Codexis’ carbon capture program.

Operating Expenses: Research and development expenses in the third quarter of 2011 were $16.8 million, compared to $13.1 million for the third quarter of 2010. The increase was primarily due to additional headcount, an increase in amortization related to intellectual property purchased from Maxygen, Inc. and stock compensation expenses. Selling, general and administrative expenses in the third quarter of 2011 increased to $8.9 million compared to $7.9 million over the same period of 2010, driven by higher stock compensation expense and higher compensation expense due to headcount increases.

Net Loss: Net loss was ($2.7) million, or ($0.08) per share, based on 35.9 million weighted average common shares outstanding in the third quarter of 2011. This compares to a net loss of ($2.7) million or ($0.08) per share during the third quarter of 2010.

Adjusted EBITDA: On a non-GAAP basis, Adjusted EBITDA increased from $2.1 million in the third quarter of 2010 to $2.6 million in 2011. Adjusted EBITDA is calculated by adjusting net loss for net interest, income taxes, depreciation, amortization, stock-based compensation and preferred stock warrant fair market valuation. A reconciliation of net loss to Adjusted EBITDA is presented below.

Cash: Cash, cash equivalents and marketable securities at September 30, 2011, decreased to $70.6 million compared to $72.4 million at June 30, 2011. The company generated $2.7 million in cash from operations in the third quarter.

 

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Outlook

Codexis’ statements with regard to its outlook are based on current expectations. The following statements are forward looking, and actual results could differ materially depending on market conditions and the factors set forth under “Forward-Looking Statements” below.

For the full year 2011, Codexis forecasts revenues of $120 million or greater, which would represent growth of 12% or greater compared to 2010. Codexis expects 2011 Adjusted EBITDA will be $5 million or greater.

Recent Events

On October 24, 2011, Codexis announced that one year after launch, its Codex® Screening Kits are in use or in evaluation in manufacturing process development at 50 pharmaceutical companies worldwide. Codex® Screening Kits were introduced in October 2010. Pharmaceutical and fine chemical companies including Merck, Roche, DSM and Dainippon Sumitomo are among the global customers using Codex® Screening Kits and Codex® Panels to reduce pharmaceutical manufacturing process development time and cost. In addition, more than 10,000 kilograms of various enzymes used in commercial pharmaceutical intermediates production processes have been manufactured by the company’s enzyme production partners.

On October 11, 2011, Codexis announced that Achilles Antonio Clement has been named Director, Latin America. Mr. Clement joined Codexis from DuPont in Latin America. He will head the newly-formed Codexis do Brasil Participacoes Ltda., Codexis’ Brazilian subsidiary, and will manage Codexis’ expanding role in Latin America.

On September 27, 2011, Codexis and Raizen Energia S.A. announced the signing of a joint development agreement to develop an improved first generation ethanol process with enhanced performance economics. Under the terms of the agreement, Raizen and Codexis will deploy the Codexis CodeEvolver(TM) directed evolution technology platform to improve Raizen’s current process for producing ethanol made from sugar.

Conference Call

Codexis will hold a conference call for investors on November 1, 2011 at 1:30 p.m. PT (4:30 p.m. ET). The conference call dial-in numbers are US: 866-788-0541 or International: 857-350-1679, access code 54501345. A live webcast of the call will also be available from the Investor Relations section of www.codexis.com. A recording of the call will be available by calling US: 888-286-8010 or International: 617-801-6888, access code 84268524 beginning approximately two hours after the call, and will be available for up to thirty days. A webcast replay from today’s call will also be available from the Investor Relations section of www.codexis.com approximately two hours after the call and will be available for up to thirty days.

About Codexis, Inc.

Codexis is an industrial biotechnology company producing high value sustainable chemicals, clean fuels, cost effective pharmaceutical processes and renewable bioindustrial ingredients to make industry more efficient, productive and profitable. Partners include global leaders such as Shell, Merck and Pfizer. For more information, see www.codexis.com.

 

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Forward-Looking Statements

This press release contains forward-looking statements relating to Codexis’ forecast for 2011 revenue and Adjusted EBITDA, and Codexis’ ability to improve Raízen’s ethanol process. You should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties and other factors that are, in some cases, beyond our control and that could materially affect actual results. Factors that could materially affect actual results include the risks that our operating results may fluctuate in the future, that we have a history of net losses and that we may be unable to successfully commercialize our technology in biofuels. Additional factors that could materially affect actual results can be found in Codexis’ Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 3, 2011, including under the caption “Risk Factors.” Codexis expressly disclaims any intent or obligation to update these forward-looking statements, except as required by law.

 

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Codexis, Inc.

Condensed Consolidated Statements of Operations

(Unaudited)

(In Thousands, Except Per Share Amounts)

 

     Three Months Ended
September 30,
          Nine Months Ended
September 30,
       
     2011     2010     % change     2011     2010     % change  

Revenues:

            

Product

   $ 12,199      $ 9,491        29   $ 33,528      $ 24,250        38

Collaborative research and development

     19,201        17,243        11     54,073        49,450        9

Government grants

     1,882        379        397     2,771        3,593        -23
  

 

 

   

 

 

     

 

 

   

 

 

   

Total revenues

     33,282        27,113        23     90,372        77,293        17
  

 

 

   

 

 

     

 

 

   

 

 

   

Costs and operating expenses:

            

Cost of product revenues

     9,958        8,563        16     28,713        19,856        45

Gross margin $

     2,241        928        141     4,815        4,394        10

Gross margin %

     18     10       14     18  

Research and development

     16,786        13,070        28     45,502        39,056        17

Selling, general and administrative

     8,871        7,940        12     27,160        25,192        8
  

 

 

   

 

 

     

 

 

   

 

 

   

Total costs and operating expenses

     35,615        29,573        20     101,375        84,104        21
  

 

 

   

 

 

     

 

 

   

 

 

   

Loss from operations

     (2,333     (2,460     -5     (11,003     (6,811     62

Interest income

     76        61        25     195        135        44

Interest expense and other, net

     (411     (35     1074     (378     (1,047     -64
  

 

 

   

 

 

     

 

 

   

 

 

   

Loss before provision for income taxes

     (2,668     (2,434     10     (11,186     (7,723     45

Provision for income taxes

     74        298        -75     68        324        -79
  

 

 

   

 

 

     

 

 

   

 

 

   

Net loss

   $ (2,742   $ (2,732     0   $ (11,254   $ (8,047     40
  

 

 

   

 

 

     

 

 

   

 

 

   

Net loss per share of common stock, basic and diluted

   $ (0.08   $ (0.08     $ (0.32   $ (0.38  
  

 

 

   

 

 

     

 

 

   

 

 

   

Weighted average common shares used in computing net loss per share of common stock, basic and diluted

     35,919        34,200          35,576        21,272     
  

 

 

   

 

 

     

 

 

   

 

 

   

 

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Codexis, Inc.

Condensed Consolidated Balance Sheets

(Unaudited)

(In Thousands)

 

     September 30,
2011
    December 31,
2010
 

Assets

    

Current assets:

    

Cash and cash equivalents

   $ 30,132      $ 72,396   

Marketable securities

     19,503        —     

Accounts receivable, net

     19,325        15,333   

Inventories

     5,240        2,817   

Prepaid expenses and other current assets

     2,837        1,646   
  

 

 

   

 

 

 

Total current assets

     77,037        92,192   

Restricted cash

     1,511        1,466   

Non-current marketable securities

     21,020        1,650   

Property and equipment, net

     23,321        21,452   

Intangible assets, net

     17,372        20,158   

Goodwill

     3,241        3,241   

Other non-current assets

     1,120        1,141   
  

 

 

   

 

 

 

Total assets

   $ 144,622      $ 141,300   
  

 

 

   

 

 

 

Liabilities and shareholders’ equity

    

Current liabilities:

    

Accounts payable

   $ 7,509      $ 9,208   

Accrued compensation

     6,165        8,107   

Other accrued liabilities

     12,100        5,630   

Deferred revenues

     8,632        4,539   
  

 

 

   

 

 

 

Total current liabilities

     34,406        27,484   

Deferred revenues, net of current portion

     1,871        5,074   

Other long-term liabilities

     1,870        1,381   
  

 

 

   

 

 

 

Total liabilities

     38,147        33,939   

Stockholders’ equity:

    

Common stock

     4        4   

Additional paid-in capital

     285,650        275,540   

Accumulated other comprehensive income (loss)

     223        (34

Accumulated deficit

     (179,402     (168,149
  

 

 

   

 

 

 

Total stockholders’ equity

     106,475        107,361   
  

 

 

   

 

 

 

Total liabilities, and shareholders’ equity

   $ 144,622      $ 141,300   
  

 

 

   

 

 

 

 

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Codexis, Inc.

Condensed Consolidated Statements of Cash Flow

(Unaudited)

(In Thousands)

 

     Nine Months Ended
September 30,
 
     2011     2010  

Operating activities:

    

Net loss

   $ (11,254   $ (8,047

Adjustments to reconcile net loss to net cash used in operating activities:

    

Amortization of intangible assets

     2,787        402   

Depreciation and amortization of property and equipment

     5,678        5,298   

Revaluation of redeemable convertible preferred stock warrant liability

     —          677   

Loss (gain) on disposal of property and equipment

     31        —     

Gain from extinguishment of asset retirement obligation

     (124     —     

Stock-based compensation

     7,393        6,466   

Accretion of asset retirement obligation

     27        —     

Amortization of debt discount

     —          70   

Accretion (amortization) of premium/discount on marketable securities

     501        511   

Changes in operating assets and liabilities:

    

Accounts receivable

     (3,991     (8,132

Inventories

     (2,423     (331

Prepaid expenses and other current assets

     (844     (213

Other assets

     20        2,602   

Accounts payable

     (1,699     (1,360

Accrued compensation

     (1,942     (472

Other accrued liabilities

     7,355        (4,247

Deferred revenues

     891        (9,276
  

 

 

   

 

 

 

Net cash provided by (used in) operating activities

     2,406        (16,052
  

 

 

   

 

 

 

Investing activities:

    

(Increase) decrease in restricted cash

     (46     65   

Purchase of property and equipment

     (7,813     (4,740

Purchase of marketable securities

     (50,900     (49,051

Proceeds from sale of marketable securities

     5,008        1,605   

Proceeds from maturities of marketable securities

     6,500        70,696   
  

 

 

   

 

 

 

Net cash provided by (used in) investing activities

     (47,251     18,575   
  

 

 

   

 

 

 

Financing activities:

    

Principal payments on financing obligations

     —          (3,979

Payments in preparation for initial public offering

     —          (3,870

Proceeds from issuance of common stock on IPO, net of underwriting discounts

     —          72,551   

Proceeds from exercises of stock options

     2,476        279   
  

 

 

   

 

 

 

Net cash provided by (used in) financing activities

     2,476        64,981   
  

 

 

   

 

 

 

Effect of exchange rate changes on cash and cash equivalents

     105        (15
  

 

 

   

 

 

 

Net increase in cash and cash equivalents

     (42,264     67,489   

Cash and cash equivalents:

    

Beginning of the period

     72,396        31,785   
  

 

 

   

 

 

 

End of the period

     30,132        99,274   

Marketable securities at the end of period

     40,523        47,306   
  

 

 

   

 

 

 

Cash, cash equivalents and marketable securities

   $ 70,655      $ 146,580   
  

 

 

   

 

 

 

Reclassification of preferred stock warrant from liability to additional paid-in capital

     $ 2,686   
    

 

 

 

Conversion of preferred stock to common stock and additional paid-in capital

     $ 179,672   
    

 

 

 

 

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Reconciliation of GAAP to Non-GAAP Financial Information

In this press release, in addition to GAAP financial results, we present Adjusted EBITDA because we believe it assists investors and analysts in comparing our performance across reporting periods on a consistent basis by excluding items that we do not believe are indicative of our core operating performance. In addition, we use Adjusted EBITDA to evaluate the effectiveness of our business strategies.

A reconciliation of GAAP net loss to Adjusted EBITDA is included in the table below.

Codexis, Inc.

Reconciliation of GAAP Net Loss to Adjusted EBITDA

(Unaudited)

(In Thousands)

 

     Three Months Ended
September 30,
    Nine Months Ended
September 30,
 

Calculation of Adjusted EBITDA

   2011     2010     2011     2010  

Net loss

   $ (2,742   $ (2,732   $ (11,254   $ (8,047

Adjustments:

        

Minus: Interest income

     (76     (61     (195     (135

Plus: Interest expense

     —          130        —          524   

Plus: Income taxes

     74        298        68        324   

Plus: Depreciation and amortization

     2,846        1,948        8,465        5,700   

Plus: Stock-based compensation

     2,536        2,548        7,393        6,466   

Plus: Preferred stock warrant fair market valuation adjustment

     —          —          —          677   
  

 

 

   

 

 

   

 

 

   

 

 

 

Adjusted EBITDA

   $ 2,638      $ 2,131      $ 4,477      $ 5,509   
  

 

 

   

 

 

   

 

 

   

 

 

 

Adjusted EBITDA has limitations as an analytical tool. Some of these limitations are:

 

   

Adjusted EBITDA does not reflect our cash expenditures, or future requirements, for capital expenditures or contractual commitments;

 

   

Adjusted EBITDA does not reflect changes in, or cash requirements for, our working capital needs;

 

   

Although depreciation and amortization are non-cash charges, the assets being depreciated and amortized will often have to be replaced in the future, and Adjusted EBITDA does not reflect any cash requirements for such replacements; and

 

   

Non-cash compensation is and will remain a key element of our overall long-term incentive compensation package, although we exclude it as an expense when evaluating our ongoing operating performance for a particular period.

Because of these limitations, Adjusted EBITDA should not be considered in isolation or as a substitute for performance measures calculated in accordance with GAAP. We compensate for these limitations by relying primarily on our GAAP results and using Adjusted EBITDA only supplementally.

Contacts:

Investors: Henk Adriaenssens, ir@codexis.com, 650-421-8331

Media: Lyn Christenson, lyn.christenson@codexis.com, 650-421-8144 or Saskia Sidenfaden, ssidenfaden@mww.com,

212-827-3771.

 

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