Resources at Codexis

Codexis ECO Synthesis™ Technology

A new paradigm in large-scale synthesis of nucleic acid therapeutics

ECO Synthesis^TM technology (Enzyme-Catalyzed Oligonucleotide Synthesis) is a proprietary new synthesis platform being developed for manufacturing modified-RNA oligonucleotide therapeutics at large-scale. Envisioned to offer a more sustainable and economically competitive manufacturing process, the platform offers novel solutions to questions of throughput and sustainability, two of the major drawbacks of the incumbent phosphoramidite chemistry.